Low Api m 10 in Commercial Honeybee Venom AIT Products Fails to Induce Prominent Humoral Responses in BALB/c Mice

While isolated rApi m 10 is immunogenic in BALB/c mice, the amount of Api m 10 in complex HBV AIT products is insufficient to induce prominent antibody responses.

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Publication Details

Journal
Journal of Investigational Allergology and Clinical Immunology
Published
2025-12-11
DOI
https://doi.org/10.18176/jiaci.1135
Primary Topic
Healthcare and Venom Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Low Api m 10 in Commercial Honeybee Venom AIT Products Fails to Induce Prominent Humoral Responses in BALB/c Mice

Vera Mahler, Ann-Christine Junker, Nicola Wagner, Detlef Bartel et al.
Journal of Investigational Allergology and Clinical Immunology
Healthcare and Venom Research
article

Low Api m 10 in Commercial Honeybee Venom AIT Products Fails to Induce Prominent Humoral Responses in BALB/c Mice

Vera Mahler, Ann-Christine Junker, Nicola Wagner, Detlef Bartel, Stefan Schülke, Franklin Kiesewetter, Sascha Döring, Sandra Schmidt, Frank Führer, Meike Arend, Jonas Lidholm, Alisa Landgraf, Kay-Martin Hanschmann, Andrew C. Eisenhauer, Michelle Beatrice Wolff, Susanne Kaul, Carola Zeigermann, Katrin E Paulus-Tremel
article en

Abstract

While isolated rApi m 10 is immunogenic in BALB/c mice, the amount of Api m 10 in complex HBV AIT products is insufficient to induce prominent antibody responses.

Journal of Investigational Allergology and Clinical ImmunologyVol. 36(6)
Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Thermo Fisher Scientific (Sweden) (SE), Universitätsklinikum Erlangen (DE), Sozialstiftung Bamberg (DE), University of Bayreuth (DE), Paul Ehrlich Institut (DE)
Openalex Percentile: Top 57%
Healthcare and Venom Research
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