Alterations of anti-SARS-CoV-2 immune response in children vary according to the nature of their immunosuppression
The intensity and the nature of the anti-viral immune alterations depend on the type and the degree of the immune impairment. Evaluating the specific host immune actors responsible for maintaining a protective response appears essential to adapt vaccine strategy in these patients, opening the door to new, more personalized vaccination approaches.
Authors
- Catherine Dollfus
- Alaa El‐Ghoneimi (ORCID: https://orcid.org/0000-0001-8133-2979)
- Marine Minier (ORCID: https://orcid.org/0000-0001-8462-2584)
- Jérôme Viala (ORCID: https://orcid.org/0000-0003-0487-2343)
- Charlotte Duneton (ORCID: https://orcid.org/0000-0002-0603-1970)
- Philippe Bidet (ORCID: https://orcid.org/0009-0009-8615-4695)
- Constance Delaugerre (ORCID: https://orcid.org/0000-0001-6081-7993)
- Matthieu Peycelon (ORCID: https://orcid.org/0000-0003-3617-4849)
- Sophie Guilmin‐Crépon (ORCID: https://orcid.org/0000-0002-6280-3162)
- Albert Faye (ORCID: https://orcid.org/0000-0003-4708-6086)
- Isabelle Nel (ORCID: https://orcid.org/0000-0002-6813-5070)
- Christine Martinez‐Vinson (ORCID: https://orcid.org/0000-0002-3010-6442)
- Guislaine Carcelain (ORCID: https://orcid.org/0000-0002-3192-3858)
- Nicolás de Roux (ORCID: https://orcid.org/0000-0002-8545-2780)
- Véronique Baudouin (ORCID: https://orcid.org/0000-0003-0242-1936)
- Pierre Frange
- Noémie Blumenthal
- Anastasia Milojkovic
- Hippolyte De Swardt
- Arnault Santonja
Institutions
- Hôpital Necker-Enfants Malades (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Robert-Debré (FR)
- Hôpital Saint-Louis (FR)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1016/j.ijid.2025.108301
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Assistance publique-Hôpitaux de Paris