Assessment of alveolar capillary membrane permeability using technetium 99m-diethylene triamine pentaacetate (Tc99m–DTPA) aerosols in patients with diffuse cutaneous systemic sclerosis – a cross-sectional study
DTPA clearance was significantly faster in dcSSc patients with ILD. Aerosol scintigraphy may detect early alveolar-capillary dysfunction before radiologic or spirometric changes. Further studies incorporating DLCO and longitudinal follow-up are warranted.
Authors
- Dharm Prakash Dwivedi (ORCID: https://orcid.org/0000-0003-0173-5538)
- Subathra Adithan (ORCID: https://orcid.org/0000-0003-1464-9911)
- Kailash Chandra (ORCID: https://orcid.org/0000-0002-4938-9622)
- Nandini Pandit
- Vishnukanth Govindaraj (ORCID: https://orcid.org/0000-0002-3854-2388)
- M. Rajaram (ORCID: https://orcid.org/0000-0001-9622-5324)
- Muniza Bai (ORCID: https://orcid.org/0000-0001-9186-1380)
- Chengappa Kavadichanda (ORCID: https://orcid.org/0000-0002-3643-3989)
- Sivaranjini Ramassamy (ORCID: https://orcid.org/0000-0002-9672-2029)
Institutions
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Publication Details
- Journal
- Expert Review of Medical Devices
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1080/17434440.2025.2603575
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00