Evaluation of osteoinductive potential of materials with BMP-2
Highly porous polylactide granules impregnated with BMP-2 demonstrated osteogenic properties in in vitro studies, and were also characterized by better osteoinductive properties compared with impregnated BMP-2 hydroxyapatite granules <i>in vivo</i>. Thus, polylactide granules with recombinant BMP-2 can be used to produce highly effective bone graft materials for the restoration of bone defects in dentistry and maxillofacial surgery.
Authors
- A. V. Vasilyev (ORCID: https://orcid.org/0000-0002-7169-2724)
- V S Kuznetsova (ORCID: https://orcid.org/0000-0001-8643-1642)
- Irina Alekseevna Nedorubova (ORCID: https://orcid.org/0000-0001-8472-7116)
- Т. Б. Бухарова (ORCID: https://orcid.org/0000-0003-0481-256X)
- Dmitry Goldshtein (ORCID: https://orcid.org/0000-0003-2438-1605)
- A. V. Gromov (ORCID: https://orcid.org/0000-0001-8815-6138)
Institutions
- Gamalei Institute of Epidemiology and Microbiology (RU)
- Central Research Institute (IN)
- Research Centre for Medical Genetics (RU)
- National Medical Research Center of Dentistry and Maxillofacial Surgery (RU)
Publication Details
- Journal
- Stomatology
- Published
- 2025-12-11
- DOI
- https://doi.org/10.17116/stomat202510406219
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00