Effect of Using Peppermint Solution on Chemotherapy Induced Oral Mucositis among adolescents with Leukemia.

Background: Acute leukemia is the most prevalent kind of cancer inchildren and adolescents. It is a malignant clonal condition affectingone or more hematopoietic system cell lines. It makes up one-thirdof all pediatric cancer cases. Aim: The study aimed to determine theeffect of using peppermint solution on chemotherapy induced oralmucositis among adolescents with leukemia. Setting: The study wasconducted at Alexandria University Children’s Hospital at Borg EL- Arab Oncology Center. Subjects and sampling: A conveniencesampling of 60 Adolescents with leukemia who were had oralmucositis. Tools: Two tools were used. Tool I: Socio-demographic andclinical data of Adolescents Assessment Sheet. Tool II: OralAssessment Guide (OAG) Tool. Results: The majority of adolescents’ ages in study and control groups ranged from 13 to 15 years (76.7%and 80% respectively). Healthy oral cavity was evident among 16.7%of adolescents in the study group compared to none of them (0.00%)in the control group. Moderate mucositis was 80.0% amongadolescents in the study group compared to 43.3% of those in thecontrol group and severe mucositis was 3.3% in study groupcompared to 56.7% in the control group with statistical significantdifference P2 = (<0.001*).Conclusion: Peppermint solution as non- pharmacological therapy effectively alleviated the oral mucositis induced chemotherapy for adolescents with leukemia.