Comparative Randomized Study of The Outcome of Single versus Two Stage Revision for Prosthetic Hip Infection

Background: Continuous debates persist on the gold standard approach for managing periprosthetic joint infection (PJI) following total hip arthroplasty (THA). Objective: This study aimed to compare the outcomes of single-stage revision versus two-stage revision for PJI after THA. Patients and methods: 40 patients were included in this study with minimum duration of follow-up of 12 months. The patients were divided into two equal groups. Group A (n=20): Single-stage revision THA. Group B (n=20): Two-stage revision THA. Infection eradication, Harris hip score (HHS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, radiological evaluation and complications were compared between the two groups. Results: There was one case of reinfection, which occurred in group B. In group A, the mean HHS was 91.70 ± 3.79 and mean WOMAC score 9.95 ± 3.78. In group B, scores were lower with mean HHS of 88.85 ± 5.31 and mean WOMAC score 15.90 ± 7.32 and complication rates were higher. There were no significant differences in radiographic outcome between the groups. Conclusion: The single-stage revision was associated with several advantages, including shorter hospital stays, reduced duration of antibiotic therapy and superior functional outcomes as well as more efficient recovery.