Optic disc melanocytoma with vitreous seeding, epiretinal membrane, systemic hypertension, and acral vitiligo: a case study

Melanocytoma is a rate benign pigmented tumor arising from melanocytes. The lesion could be found intraocularly at any age, but the average age is 50 years with a slight female predilection (63% of the cases). Although most tumors are asymptomatic, some patients may develop visual symptoms caused by neural, vascular compression, or tumor necrosis. A 69-year-old female patient presented for checking of her glasses. A routine fundus examination revealed a pigmented dark brown lesion partially obscuring the optic nerve head, along with the presence of vitreous floaters. A provisional diagnosis of optic disc melanocytoma (ODMC) was subsequently confirmed through B-scan ultrasonography and optical coherence tomography imaging. The patient also exhibited systemic associations, including systemic hypertension and acral vitiligo. This report highlights the uncommon association of ODMC with vitreous seeding, epiretinal membrane formation, systemic hypertension, and the first documented case of ODMC associated with acral vitiligo.

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Publication Details

Journal
Delta Journal of Ophthalmology
Published
2025-10-01
DOI
https://doi.org/10.4103/djo.djo_6_25
Primary Topic
Ocular Oncology and Treatments
Type
article
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article

Optic disc melanocytoma with vitreous seeding, epiretinal membrane, systemic hypertension, and acral vitiligo: a case study

Yasmeen Mohamed Mohamed Ghazy, Mohamed Elshafie
Delta Journal of Ophthalmology
Ocular Oncology and Treatments
article

Optic disc melanocytoma with vitreous seeding, epiretinal membrane, systemic hypertension, and acral vitiligo: a case study

Yasmeen Mohamed Mohamed Ghazy, Mohamed Elshafie
article en

Abstract

Melanocytoma is a rate benign pigmented tumor arising from melanocytes. The lesion could be found intraocularly at any age, but the average age is 50 years with a slight female predilection (63% of the cases). Although most tumors are asymptomatic, some patients may develop visual symptoms caused by neural, vascular compression, or tumor necrosis. A 69-year-old female patient presented for checking of her glasses. A routine fundus examination revealed a pigmented dark brown lesion partially obscuring the optic nerve head, along with the presence of vitreous floaters. A provisional diagnosis of optic disc melanocytoma (ODMC) was subsequently confirmed through B-scan ultrasonography and optical coherence tomography imaging. The patient also exhibited systemic associations, including systemic hypertension and acral vitiligo. This report highlights the uncommon association of ODMC with vitreous seeding, epiretinal membrane formation, systemic hypertension, and the first documented case of ODMC associated with acral vitiligo.

Delta Journal of OphthalmologyVol. 26(4)
Kafrelsheikh University (EG)
Openalex Percentile: Top 46%
Ocular Oncology and Treatments
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