Ocular graft-versus-host disease: a case report

Graft-versus-host disease is a common complication after allogeneic hematopoietic stem cell transplantation. Severe ocular involvement may be present, which requires systemic management and multiple interventions by the Ophthalmologist, including pharmacological and surgical approaches. This case highlights the complications through the medical management of a patient with ocular graft-versus-host disease. Despite multiple interventions aiming at visual rehabilitation and preservation that provided short-term benefits, the disease persistence hindered the definitive therapeutic control, which enhances the need to explore future treatment options.

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Publication Details

Journal
Delta Journal of Ophthalmology
Published
2025-10-01
DOI
https://doi.org/10.4103/djo.djo_3_25
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
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article

Ocular graft-versus-host disease: a case report

Lucie F. Calderon, Sebastián Forero Amézquita, María C. Garzón Viasus, Tatiana V. Perdomo et al.
Delta Journal of Ophthalmology
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article

Ocular graft-versus-host disease: a case report

Lucie F. Calderon, Sebastián Forero Amézquita, María C. Garzón Viasus, Tatiana V. Perdomo, Lisseth M.N. Jauregui Villamizar, Germán F. Echandía
article en

Abstract

Graft-versus-host disease is a common complication after allogeneic hematopoietic stem cell transplantation. Severe ocular involvement may be present, which requires systemic management and multiple interventions by the Ophthalmologist, including pharmacological and surgical approaches. This case highlights the complications through the medical management of a patient with ocular graft-versus-host disease. Despite multiple interventions aiming at visual rehabilitation and preservation that provided short-term benefits, the disease persistence hindered the definitive therapeutic control, which enhances the need to explore future treatment options.

Delta Journal of OphthalmologyVol. 26(4)
Universidad de La Sabana (CO), Hospital Universitario de la Samaritana (CO)
Openalex Percentile: Top 40%
Hematopoietic Stem Cell Transplantation
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