Clinical Characteristics of Granular Parakeratosis Caused by Benzalkonium Chloride: A Retrospective Case Series

BAK can induce GP, which presents with certain characteristic features, notably the presence of parchment-like scaling that serves as a valuable clue for differential diagnosis. Early identification and elimination of the causative irritant are key to effective treatment. Pediatric patients may be more susceptible, and the development of GP may be related to individual predisposition and cumulative BAK exposure, warranting further investigation.

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Publication Details

Journal
Clinical Cosmetic and Investigational Dermatology
Published
2025-12-01
DOI
https://doi.org/10.2147/ccid.s558977
Primary Topic
Environmental Chemistry and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical Characteristics of Granular Parakeratosis Caused by Benzalkonium Chloride: A Retrospective Case Series

Shisheng Chen, Yingwei Wang, Fan Lin
Clinical Cosmetic and Investigational Dermatology
Environmental Chemistry and Analysis
article

Clinical Characteristics of Granular Parakeratosis Caused by Benzalkonium Chloride: A Retrospective Case Series

Shisheng Chen, Yingwei Wang, Fan Lin
article en

Abstract

BAK can induce GP, which presents with certain characteristic features, notably the presence of parchment-like scaling that serves as a valuable clue for differential diagnosis. Early identification and elimination of the causative irritant are key to effective treatment. Pediatric patients may be more susceptible, and the development of GP may be related to individual predisposition and cumulative BAK exposure, warranting further investigation.

Clinical Cosmetic and Investigational DermatologyVol. Volume 18
Wenzhou Medical University (CN), Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Openalex Percentile: Top 65%
Environmental Chemistry and Analysis
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