Acute rectal calcinosis following parathyroidectomy in a patient with primary hyperparathyroidism and preoperative hypercalcaemic crisis

Severe hypercalcaemia can lead to visceral calcifications, ischaemic changes, and gastrointestinal complications, even if not initially evident. In patients with primary hyperparathyroidism, acute rectal bleeding following parathyroidectomy may indicate a rare cause such as rectal calcinosis and should be considered in the differential diagnosis. Calcinosis should be particularly suspected in cases with a severe clinical picture of hyperparathyroidism-related hypercalcaemia (e.g. severe weight loss, lack of calcium correction after standard therapy). Early diagnosis and conservative management can result in favourable outcomes without the need for invasive treatment.

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Publication Details

Journal
Endocrinology Diabetes and Metabolism Case Reports
Published
2025-10-01
DOI
https://doi.org/10.1530/edm-25-0100
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Acute rectal calcinosis following parathyroidectomy in a patient with primary hyperparathyroidism and preoperative hypercalcaemic crisis

Helēna Apele, Dace Seisuma
Endocrinology Diabetes and Metabolism Case Reports
Parathyroid Disorders and Treatments
article

Acute rectal calcinosis following parathyroidectomy in a patient with primary hyperparathyroidism and preoperative hypercalcaemic crisis

Helēna Apele, Dace Seisuma
article en

Abstract

Severe hypercalcaemia can lead to visceral calcifications, ischaemic changes, and gastrointestinal complications, even if not initially evident. In patients with primary hyperparathyroidism, acute rectal bleeding following parathyroidectomy may indicate a rare cause such as rectal calcinosis and should be considered in the differential diagnosis. Calcinosis should be particularly suspected in cases with a severe clinical picture of hyperparathyroidism-related hypercalcaemia (e.g. severe weight loss, lack of calcium correction after standard therapy). Early diagnosis and conservative management can result in favourable outcomes without the need for invasive treatment.

Endocrinology Diabetes and Metabolism Case ReportsVol. 2025(4)
Pauls Stradiņš Clinical University Hospital (LV), Riga Stradiņš University (LV)
Openalex Percentile: Top 51%
Parathyroid Disorders and Treatments
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