Anaysis of the association between chromosomal abnormalities in early missed abortion embryos and maternal age and AMH levels based on CNV-Seq

Increased maternal age and decreased AMH levels are closely associated with higher risk of chromosomal abnormalities in EMA embryos. As a sensitive indicator of ovarian reserve, AMH reflects oocyte quality and chromosomal stability, particularly in younger women. Combined assessment of maternal age and AMH may improve risk evaluation and inform preventive and intervention strategies for EMA.

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Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2025-12-09
DOI
https://doi.org/10.1186/s12884-025-08562-4
Primary Topic
Prenatal Screening and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Anaysis of the association between chromosomal abnormalities in early missed abortion embryos and maternal age and AMH levels based on CNV-Seq

Danping Liu, Shuhui Huang, Huizhen Yuan, Baitao Zeng et al.
BMC Pregnancy and Childbirth
Prenatal Screening and Diagnostics
article

Anaysis of the association between chromosomal abnormalities in early missed abortion embryos and maternal age and AMH levels based on CNV-Seq

Danping Liu, Shuhui Huang, Huizhen Yuan, Baitao Zeng, Tingting Huang, Yujie Zhou, Guiqin Bai
article en

Abstract

Increased maternal age and decreased AMH levels are closely associated with higher risk of chromosomal abnormalities in EMA embryos. As a sensitive indicator of ovarian reserve, AMH reflects oocyte quality and chromosomal stability, particularly in younger women. Combined assessment of maternal age and AMH may improve risk evaluation and inform preventive and intervention strategies for EMA.

BMC Pregnancy and ChildbirthVol. 26(1)
Jiangxi Maternal and Child Health Hospital (CN), Xi'an Jiaotong University (CN)
Openalex Percentile: Top 50%
Prenatal Screening and Diagnostics
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