Pouch excision, dysplasia and polypectomy in familial adenomatous polyposis ileal pouch anal anastomosis: a retrospective analysis

Patients with FAP and IPAA require surveillance due to a high incidence of dysplasia and polyp formation, although malignancy remains rare. There is a significant rate of pouch excision, for which pouchitis appears to be a risk factor. Early and aggressive endoscopic management of polyps is recommended to prevent advanced disease and minimise complications associated with surgical approaches.

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Publication Details

Journal
BMJ Open Gastroenterology
Published
2025-12-01
DOI
https://doi.org/10.1136/bmjgast-2025-001758
Primary Topic
Genetic factors in colorectal cancer
Type
article
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article

Pouch excision, dysplasia and polypectomy in familial adenomatous polyposis ileal pouch anal anastomosis: a retrospective analysis

Ahsan Javed, Iain Blake, Hina Aslam, Shakil Ahmed et al.
BMJ Open Gastroenterology
Genetic factors in colorectal cancer
article

Pouch excision, dysplasia and polypectomy in familial adenomatous polyposis ileal pouch anal anastomosis: a retrospective analysis

Ahsan Javed, Iain Blake, Hina Aslam, Shakil Ahmed, Paul Collins
article en

Abstract

Patients with FAP and IPAA require surveillance due to a high incidence of dysplasia and polyp formation, although malignancy remains rare. There is a significant rate of pouch excision, for which pouchitis appears to be a risk factor. Early and aggressive endoscopic management of polyps is recommended to prevent advanced disease and minimise complications associated with surgical approaches.

BMJ Open GastroenterologyVol. 12(1)
University of Liverpool (GB), Aintree University Hospitals NHS Foundation Trust (GB), Liverpool Womens NHS Foundation Trust (GB), Liverpool John Moores University (GB)
Openalex Percentile: Top 45%
Genetic factors in colorectal cancer
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Pouch excision, dysplasia and polypectomy in familial adenomatous polyposis ileal pouch anal anastomosis: a retrospective analysis — Ahsan Javed, Iain Blake, et al. · BMJ Open Gastroenterology (2025) | TGRS Research Map | TGRS