A Case Report of Short‐Term Metastasis After Surgery for Mammary Paget's Disease

Mammary Paget's disease (MPD) with ductal carcinoma in situ (DCIS) pathology can metastasize rapidly. HER2-positive status likely drives aggression, warranting early postoperative systemic imaging and close surveillance. Anti-HER2 agents require proactive toxicity management. Personalized dose adjustments and multidisciplinary management are essential to optimize outcomes.

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Publication Details

Journal
Clinical Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1002/ccr3.71585
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case Report of Short‐Term Metastasis After Surgery for Mammary Paget's Disease

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Clinical Case Reports
Cancer and Skin Lesions
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A Case Report of Short‐Term Metastasis After Surgery for Mammary Paget's Disease

Ming Yan, Chao Wang, Xiaofang Gao, Dongxu Li, Jing Wang, Jiahui Zhou, Yong Pan
article en

Abstract

Mammary Paget's disease (MPD) with ductal carcinoma in situ (DCIS) pathology can metastasize rapidly. HER2-positive status likely drives aggression, warranting early postoperative systemic imaging and close surveillance. Anti-HER2 agents require proactive toxicity management. Personalized dose adjustments and multidisciplinary management are essential to optimize outcomes.

Clinical Case ReportsVol. 13(12)
Peking University (CN), Peking University Cancer Hospital (CN)
Openalex Percentile: Top 37%
Cancer and Skin Lesions
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