Danon disease presenting with atypical non-septal sparing LGE on cardiac MRI: a case report

This case demonstrates that Danon disease can manifest in young patients with a specific CMR pattern-even in the absence of classic structural changes such as left ventricular hypertrophy. Therefore, clinicians should include Danon disease in the differential diagnosis for paediatric patients presenting with a combination of unexplained elevated biomarkers, electrical abnormalities, and distinctive LGE. Early genetic testing is critical in such scenarios to confirm or exclude the diagnosis.