The mysterious joint: Septic arthritis and acute osteomyelitis due to Fusarium species in a child with type II Chiari malformation

Fungal bone infection due to Fusarium species is unusual. We report a case of a child who presented with septic arthritis and osteomyelitis due to Fusarium species. The lack of clinical trials and the organism’s intrinsic resistance to most antifungal agents make antimicrobial management difficult. Our patient attained a favourable response to therapy with amphotericin B and voriconazole. This case report highlights a rare manifestation of joint- and bone-related Fusarium infection in a child.

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Publication Details

Journal
South African Medical Journal
Published
2025-12-08
DOI
https://doi.org/10.7196/samj.2025.v115i11.3194
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

The mysterious joint: Septic arthritis and acute osteomyelitis due to Fusarium species in a child with type II Chiari malformation

Prasha Mahabeer, S Govender, Leatitia Kampiire, Kagiso Mochankana et al.
South African Medical Journal
Antifungal resistance and susceptibility
article

The mysterious joint: Septic arthritis and acute osteomyelitis due to Fusarium species in a child with type II Chiari malformation

Prasha Mahabeer, S Govender, Leatitia Kampiire, Kagiso Mochankana, Khine Swe Swe-Han, Moherndran Archary, N Brijlal
article en

Abstract

Fungal bone infection due to Fusarium species is unusual. We report a case of a child who presented with septic arthritis and osteomyelitis due to Fusarium species. The lack of clinical trials and the organism’s intrinsic resistance to most antifungal agents make antimicrobial management difficult. Our patient attained a favourable response to therapy with amphotericin B and voriconazole. This case report highlights a rare manifestation of joint- and bone-related Fusarium infection in a child.

South African Medical Journal
National Health Laboratory Service (ZA), University of KwaZulu-Natal (ZA)
Openalex Percentile: Top 54%
Antifungal resistance and susceptibility
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The mysterious joint: Septic arthritis and acute osteomyelitis due to Fusarium species in a child with type II Chiari malformation — Prasha Mahabeer, S Govender, et al. · South African Medical Journal (2025) | TGRS Research Map | TGRS