Extra-Axial Cerebellopontine Angle Low Grade Glioma – Unusual Occurrence in a 43-year-old Woman

Cerebellopontine angle (CPA) is an anatomical space of posterior cranial fossa bounded by tentorium superiorly, pons and cerebellum posteriorly and temporal bone anterolaterally. Glial cell tumors are located frequently in the cerebral hemispheres, while vestibular Schwannoma, meningioma and epidermoid cysts frequently affect the CPA. Low-grade gliomas (LGGs) presenting as a space occupying lesion (SOL) in cerebellopontine angle (CPA) is an extremely rare occurrence. This study reports a 43-year-old female, with no comorbidities, who presented with the chief complaints of headache and walking difficulty for six weeks, associated with left-sided facial numbness and hearing impairment. Neuro-imaging revealed left CPA SOL, which was excised via retrosigmoid craniectomy. Pathological work up was suggestive of diffuse low-grade glioma. The development of atypical SOLs, like glioma in this case, should be considered in the differential diagnosis of cerebellopontine angle tumors. The standard treatment is maximum safe resection in case of LGGs with serial neuroimaging and adjuvant management.

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Publication Details

Journal
Pakistan Journal of Medical Sciences
Published
2025-12-09
DOI
https://doi.org/10.12669/pjms.41.13(pins-nnos).13492
Primary Topic
Meningioma and schwannoma management
Type
article
Field-Weighted Citation Impact
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article

Extra-Axial Cerebellopontine Angle Low Grade Glioma – Unusual Occurrence in a 43-year-old Woman

Sumira Kiran, Muhammad Jamil, Zubair Mustafa Khan, Sameed Safdar Sheikh
Pakistan Journal of Medical Sciences
Meningioma and schwannoma management
article

Extra-Axial Cerebellopontine Angle Low Grade Glioma – Unusual Occurrence in a 43-year-old Woman

Sumira Kiran, Muhammad Jamil, Zubair Mustafa Khan, Sameed Safdar Sheikh
article en

Abstract

Cerebellopontine angle (CPA) is an anatomical space of posterior cranial fossa bounded by tentorium superiorly, pons and cerebellum posteriorly and temporal bone anterolaterally. Glial cell tumors are located frequently in the cerebral hemispheres, while vestibular Schwannoma, meningioma and epidermoid cysts frequently affect the CPA. Low-grade gliomas (LGGs) presenting as a space occupying lesion (SOL) in cerebellopontine angle (CPA) is an extremely rare occurrence. This study reports a 43-year-old female, with no comorbidities, who presented with the chief complaints of headache and walking difficulty for six weeks, associated with left-sided facial numbness and hearing impairment. Neuro-imaging revealed left CPA SOL, which was excised via retrosigmoid craniectomy. Pathological work up was suggestive of diffuse low-grade glioma. The development of atypical SOLs, like glioma in this case, should be considered in the differential diagnosis of cerebellopontine angle tumors. The standard treatment is maximum safe resection in case of LGGs with serial neuroimaging and adjuvant management.

Pakistan Journal of Medical SciencesVol. 41(13(PINS-NNOS))
Punjab Institute of Cardiology (PK), Allama Iqbal Medical College (PK), Post Graduate Medical Institute (PK)
Openalex Percentile: Top 49%
Meningioma and schwannoma management
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