Cutaneous Opportunistic Mycobacterial and Fungal Infections in Adult-Onset Immunodeficiency Due to Anti-Interferon-Gamma Autoantibodies—Decoding Skin Involvement Patterns

Cutaneous lesions involving the neck area and lymphadenopathy are clinical clues that suggest cutaneous <i>Mycobacterium</i> OIs. Nevertheless, integration of clinical features with laboratory findings enables the development of a predictive model that can effectively differentiate between cutaneous mycobacterial and fungal infections. This predictive model may aid in selecting appropriate empirical antimicrobial therapy, particularly when microbiological confirmation is pending or inconclusive despite high clinical suspicion.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-11-26
DOI
https://doi.org/10.1093/ofid/ofaf739
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
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article

Cutaneous Opportunistic Mycobacterial and Fungal Infections in Adult-Onset Immunodeficiency Due to Anti-Interferon-Gamma Autoantibodies—Decoding Skin Involvement Patterns

Atibordee Meesing, Napatra Tovanabutra, Salin Kiratikanon, Romanee Chaiwarith et al.
Open Forum Infectious Diseases
Immunodeficiency and Autoimmune Disorders
article

Cutaneous Opportunistic Mycobacterial and Fungal Infections in Adult-Onset Immunodeficiency Due to Anti-Interferon-Gamma Autoantibodies—Decoding Skin Involvement Patterns

Atibordee Meesing, Napatra Tovanabutra, Salin Kiratikanon, Romanee Chaiwarith, Nayanunt Prinyaroj, Suteeraporn Chaowattanapanit, Charoen Choonhakarn, Mati Chuamanochan, Siri Chiewchanvit, Rujira Rujiwetpongstorn, Phichayut Pinyo
article en

Abstract

Cutaneous lesions involving the neck area and lymphadenopathy are clinical clues that suggest cutaneous <i>Mycobacterium</i> OIs. Nevertheless, integration of clinical features with laboratory findings enables the development of a predictive model that can effectively differentiate between cutaneous mycobacterial and fungal infections. This predictive model may aid in selecting appropriate empirical antimicrobial therapy, particularly when microbiological confirmation is pending or inconclusive despite high clinical suspicion.

Open Forum Infectious DiseasesVol. 12(12)
Khon Kaen University (TH), Chiang Mai University (TH)
Openalex Percentile: Top 55%
Immunodeficiency and Autoimmune Disorders
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Cutaneous Opportunistic Mycobacterial and Fungal Infections in Adult-Onset Immunodeficiency Due to Anti-Interferon-Gamma Autoantibodies—Decoding Skin Involvement Patterns — Atibordee Meesing, Napatra Tovanabutra, et al. · Open Forum Infectious Diseases (2025) | TGRS Research Map | TGRS