Topical retinoid use in women of reproductive age and risk of major congenital malformations in exposed pregnancies: a Nordic cohort study
We observed a 3.3-fold increase in topical retinoid use over the past 18 years among women of reproductive age in the Nordic countries. We did not observe an increased risk of MCM associated with use of topical retinoids. Limiting to pregnancies resulting in a birth could underestimate both the prevalence of topical retinoid exposure and MCM risk.
Authors
- Kari Furu (ORCID: https://orcid.org/0000-0003-2245-0179)
- Felix Wittström (ORCID: https://orcid.org/0000-0001-6845-6774)
- Sinna Pilgaard Ulrichsen (ORCID: https://orcid.org/0000-0001-8679-5163)
- Jacqueline M. Cohen (ORCID: https://orcid.org/0000-0002-7300-0488)
- Mette Nørgaard (ORCID: https://orcid.org/0000-0001-6110-5891)
- Erle Refsum (ORCID: https://orcid.org/0000-0002-9591-5152)
- Carolyn E. Cesta (ORCID: https://orcid.org/0000-0001-5759-9366)
- Helga Zoëga (ORCID: https://orcid.org/0000-0003-0761-9028)
Institutions
- Norwegian Institute of Public Health (NO)
- University of Iceland (IS)
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Karolinska Institutet (SE)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-12-05
- DOI
- https://doi.org/10.1093/bjd/ljaf500
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00