Comparing nab-paclitaxel and solvent-based paclitaxel in platinum-resistant ovarian cancer: evidence and perspectives

Despite the absence of direct trials, experts considered evidence sufficient to support nab-paclitaxel as a viable alternative to sb-paclitaxel in platinum-resistant ovarian cancer with comparable efficacy, safety, and fewer hypersensitivity reactions. Additional randomized trials were not deemed necessary.

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Publication Details

Journal
International Journal of Gynecological Cancer
Published
2025-12-01
DOI
https://doi.org/10.1016/j.ijgc.2025.102841
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparing nab-paclitaxel and solvent-based paclitaxel in platinum-resistant ovarian cancer: evidence and perspectives

Jalid Sehouli, Jolijn Boer, Christina Fotopoulou, Alexander Krannich et al.
International Journal of Gynecological Cancer
Ovarian cancer diagnosis and treatment
article

Comparing nab-paclitaxel and solvent-based paclitaxel in platinum-resistant ovarian cancer: evidence and perspectives

Jalid Sehouli, Jolijn Boer, Christina Fotopoulou, Alexander Krannich, Robert Louis Coleman, Meghan R. Forrest, Giorgio Bogani, Matthias Rose, Chisato Ito, Tobias Kurth, Franziska Sinn, Pauline Wimberger, Elena Fischer, Jacek Grabowski, Susanne Fechner, Gülten Oskay-Öczelik, Andrea Krull, Bradley Monk, Thomas Ecker, Ainhoa Madariaga
article en

Abstract

Despite the absence of direct trials, experts considered evidence sufficient to support nab-paclitaxel as a viable alternative to sb-paclitaxel in platinum-resistant ovarian cancer with comparable efficacy, safety, and fewer hypersensitivity reactions. Additional randomized trials were not deemed necessary.

International Journal of Gynecological Cancer
The University of Texas MD Anderson Cancer Center (US), Hammersmith Hospital (GB), Research Institute Hospital 12 de Octubre (ES), German Cancer Society (DE), Asklepios Fachklinikum Tiefenbrunn (DE), Florida Cancer Specialists & Research Institute (US), Cancer Clinic (US), Nord-Ostdeutsche Gesellschaft für Gynäkologische Onkologie (DE), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), University Hospital Carl Gustav Carus (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 49%
Ovarian cancer diagnosis and treatment
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