From dysphoria to anhedonia: age-related shift in the link between cognitive and affective symptoms
Cognitive-affective bridging symptoms differ with age, with anhedonia replacing dysphoria as the key bridge in older adults. This shift was linked to age-related differences in the relationship between GMV, cognition, and depressive symptoms. These results highlight the need to target different symptoms to alleviate cognitive-affective manifestations across the lifespan.
Authors
- Daniel Harlev (ORCID: https://orcid.org/0000-0001-9733-707X)
- Moni Shahar
- Aya Vituri (ORCID: https://orcid.org/0000-0002-6281-6350)
- Noham Wolpe (ORCID: https://orcid.org/0000-0002-4652-7727)
Institutions
- Tel Aviv University (IL)
- Rambam Health Care Campus (IL)
Publication Details
- Journal
- The Journals of Gerontology Series B
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1093/geronb/gbaf252
- Primary Topic
- Psychosomatic Disorders and Their Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00