Expression of Poliovirus Receptor, the Ligand of TIGIT, Associated With Immune-Cold Tumor Microenvironment in Hepatocellular Carcinoma
HCC tissues with high PVR expression were more common in metastatic disease and were associated with an immune-cold TME. These findings may have implications for the development of immunotherapies for HCC.
Authors
- Shuhan Yang (ORCID: https://orcid.org/0009-0005-2310-6654)
- Ann‐Lii Cheng (ORCID: https://orcid.org/0000-0002-9152-6512)
- Tsung‐Hao Liu (ORCID: https://orcid.org/0000-0002-8891-4426)
- Yu‐Yun Shao (ORCID: https://orcid.org/0000-0001-7334-1912)
- Li‐Chun Lu (ORCID: https://orcid.org/0000-0001-8975-9491)
- Chih‐Hung Hsu (ORCID: https://orcid.org/0000-0003-0495-973X)
- Yi‐Hsuan Lee (ORCID: https://orcid.org/0000-0002-2995-8306)
Institutions
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1200/po-25-00639
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00