Bufalin alleviates myocardial ischemia-reperfusion injury by targeting PTGR2 to regulate NF-κB mediated inflammation
These findings suggest Bufalin alleviates MIRI by targeting PTGR2 to regulate C1QTNF3/NF-κB signaling, providing a candidate for MIRI treatment.
Authors
- Teng Ge
- Rongjun Zou (ORCID: https://orcid.org/0000-0003-1981-5472)
- Liangbing Yang
- Kanglai He (ORCID: https://orcid.org/0000-0001-5959-1042)
- Jinlin Hu (ORCID: https://orcid.org/0000-0002-2909-0308)
- Miao Zhang (ORCID: https://orcid.org/0000-0003-4912-2570)
- Guang Li (ORCID: https://orcid.org/0000-0002-0795-7396)
- Jie Lin (ORCID: https://orcid.org/0000-0003-3535-5250)
- Chaojie Wang (ORCID: https://orcid.org/0000-0002-5916-3547)
- Xiaoping Fan (ORCID: https://orcid.org/0000-0002-7067-7450)
- Jian Bo (ORCID: https://orcid.org/0000-0003-0285-8775)
- Bo Ning (ORCID: https://orcid.org/0000-0002-0105-1972)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Fudan University (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
- Zhongshan Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.biopha.2025.118895
- Primary Topic
- NF-κB Signaling Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00