Progressive Fibrosis in Hydroxychloroquine Cardiomyopathy Mimicking Hypertrophic Cardiomyopathy and Cardiac Amyloidosis

Hydroxychloroquine cardiotoxicity should be considered when pyrophosphate scintigraphy is positive in patients with long-term exposure. Early recognition (before extensive fibrosis develops) is critical, as the likelihood of recovery diminishes with advanced disease.

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Publication Details

Journal
JACC Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1016/j.jaccas.2025.105857
Citations
1
Primary Topic
Drug-Induced Ocular Toxicity
Type
article
Field-Weighted Citation Impact
1.71
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article

Progressive Fibrosis in Hydroxychloroquine Cardiomyopathy Mimicking Hypertrophic Cardiomyopathy and Cardiac Amyloidosis

Yinong Wang, Nowell Mark Fine, Robert J.H. Miller, Zainab Altaha et al.
1 citations
JACC Case Reports
Drug-Induced Ocular Toxicity
1.71
article

Progressive Fibrosis in Hydroxychloroquine Cardiomyopathy Mimicking Hypertrophic Cardiomyopathy and Cardiac Amyloidosis

Yinong Wang, Nowell Mark Fine, Robert J.H. Miller, Zainab Altaha, Omid Kiamanesh, Xi Zhao
article en
1 citations

Abstract

Hydroxychloroquine cardiotoxicity should be considered when pyrophosphate scintigraphy is positive in patients with long-term exposure. Early recognition (before extensive fibrosis develops) is critical, as the likelihood of recovery diminishes with advanced disease.

JACC Case ReportsVol. 30(40)
University of Calgary (CA), Libin Cardiovascular Institute of Alberta (CA)
Openalex Percentile: Top 12%
Drug-Induced Ocular Toxicity
1.71
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