Design and Synthesis of Symmetric Bis Schiff Base as Potential Anti‐Cancer Agent and Selective Chemosensor for Sn(II) Detection

ABSTRACT In this research article, we have successfully synthesized a Symmetric Bis Schiff Base compound and it was thoroughly characterized utilizing various spectroscopic techniques such as proton ( 1 H) NMR, carbon ( 13 C) NMR, and mass spectrometry. Compound DSB was found to detect very selectivity Sn(II) as determined through UV–visible spectroscopy. The greater sensitivity of DSB toward Sn(II) was evident as the value of limit of detection (LOD) came out to be 82.31 nM. Additionally, Job's plot supported 1:1 stoichiometric binding of DSB and Sn(II). In addition to its sensing ability, the compound demonstrated noteworthy anti‐cancer activity, evaluated through both in vitro experiments and molecular docking studies. This versatile strategy, encompassing Sn(II) detection, and anti‐cancer potential, highlights the promise of this Symmetric Bis Schiff Base chemosensor as an effective tool for applications in both environmental monitoring and biomedical research.