Hepatocyte-Targeted Epicatechin Nanoparticles Promote Autophagy and Enhance Mitochondrial Function in Metabolic Dysfunction-Associated Steatotic Liver Disease
Our findings highlight EC@PLGA-PEG-GAL NPs as promising liver-targeted nanotherapeutics simultaneously modulating autophagy and mitochondrial functions in metabolic dysfunction-associated steatotic liver disease.
Authors
- Jongdae Shin
- Hyeji Lee (ORCID: https://orcid.org/0000-0002-6584-1471)
- Daewon Han (ORCID: https://orcid.org/0000-0001-9731-5620)
- Kyubae Lee (ORCID: https://orcid.org/0000-0002-1270-8554)
- Tae‐Eun Jin (ORCID: https://orcid.org/0000-0001-9405-7611)
- Junguee Lee (ORCID: https://orcid.org/0000-0002-1477-1418)
- Solji Lee
- Hwan‐Woo Park (ORCID: https://orcid.org/0000-0001-8029-2004)
- Do Kyung Kim (ORCID: https://orcid.org/0000-0001-6655-7061)
- Jong-Seok Kim (ORCID: https://orcid.org/0000-0002-0998-5569)
- Nam-Kyung Lee (ORCID: https://orcid.org/0000-0001-8348-4773)
Institutions
- Daejeon University (KR)
- Konyang University (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/ijn.s557902
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00