Continuous Physiologic Markers of Heart Rate Variability Derived From Bedside Electrocardiogram Precede Onset of Acute Respiratory Distress Syndrome: A Physiologic Modeling Study
Waveform markers can combine with Electronic Medical Records (EMR) data to improve predictability of ARDS before onset. The markers appear to modulate the sparser EMR data. They also provide, in and of themselves, sufficient dynamical information for comparable results to models with EMR data. Further prospective validation is needed to evaluate the robustness of the model and potential clinical utility.
Authors
- Joao Gabriel De Souza Vale
- Eric A. Elster (ORCID: https://orcid.org/0000-0002-0981-2748)
- Rishikesan Kamaleswaran (ORCID: https://orcid.org/0000-0001-8366-4811)
- Ayman Ali (ORCID: https://orcid.org/0000-0002-2791-2793)
- Saideep Narendrula
- Haoming Shi (ORCID: https://orcid.org/0000-0002-0228-6116)
- Preethi Krishnan (ORCID: https://orcid.org/0000-0001-6957-385X)
- Simon Tallowin (ORCID: https://orcid.org/0000-0002-3203-4104)
- T. Buchmann
- Philip Yang (ORCID: https://orcid.org/0000-0001-5142-1137)
- Curtis Marshall
- Christopher J. Dente
- A. Gent (ORCID: https://orcid.org/0000-0001-7429-3828)
- Seth Schobel (ORCID: https://orcid.org/0000-0002-8967-257X)
- Carolyn Davis (ORCID: https://orcid.org/0000-0002-0760-1381)
- Felipe Lisboa (ORCID: https://orcid.org/0009-0002-8733-3889)
- Victor M. Moas
- Jeffrey Wang (ORCID: https://orcid.org/0000-0002-2864-2115)
- J. Song (ORCID: https://orcid.org/0000-0001-9699-1029)
- Hayoung Jeong (ORCID: https://orcid.org/0000-0002-0359-8218)
Institutions
- Henry M. Jackson Foundation (US)
- Georgia Institute of Technology (US)
- Uniformed Services University of the Health Sciences (US)
- Emory University (US)
- Duke University (US)
- Walter Reed National Military Medical Center (US)
- Royal Navy (GB)
- The Wallace H. Coulter Department of Biomedical Engineering (US)
Publication Details
- Journal
- Critical Care Explorations
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1097/cce.0000000000001352
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00