A narrative review on the therapeutic potential of stem cells in neurodegenerative diseases: advances, insights, and challenges
Regardless of their potential, stem cell therapies raise health risks, including neoplastic growth and immunological incompatibility, alongside bioethical issues. Developments in genetic modification, nanotechnology, and preconditioning strategies are being analyzed to optimize outcomes. Long-term research, harmonization of protocols, and extended patient follow-up are essential for the safe and effective development of medical applications.
Authors
- Tirath Patel (ORCID: https://orcid.org/0009-0002-8099-238X)
- Iman Sharif
- Habib Sharif (ORCID: https://orcid.org/0000-0001-5860-5836)
- Shaheryar Usman (ORCID: https://orcid.org/0009-0006-8376-7590)
- M K Javaid (ORCID: https://orcid.org/0000-0001-7985-0048)
- Nikhilesh Anand (ORCID: https://orcid.org/0000-0002-2986-3550)
- Christopher Hanani
- Fatima Mustafa (ORCID: https://orcid.org/0000-0002-6801-5941)
- Fathimathul Henna
- Fatima Nasir
- Inaya Javed
Institutions
- Henry Ford Health System (US)
- Trinity School of Medicine (VC)
- The University of Texas Rio Grande Valley (US)
- Farooq Hospital (PK)
- Dubai Medical College (AE)
Publication Details
- Journal
- Annals of Medicine and Surgery
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1097/ms9.0000000000004490
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00