Construction of a Risk Factor Model for Wound Infection After Ileostomy for Rectal Cancer and Its Relationship with Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 (NLRP3) Gene Polymorphism

This study identified the independent risk factors for postoperative wound infection. Patients with the G allele have a higher risk of postoperative infection, and <i>NLRP3</i> gene polymorphism is closely associated with the risk factors included in the model. The association between <i>NLRP3</i> gene polymorphisms and the risk of postoperative infection provides a new molecular biological indicator for prognostic evaluation.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-12-01
DOI
https://doi.org/10.2147/idr.s535810
Primary Topic
Immune Response and Inflammation
Type
article
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article

Construction of a Risk Factor Model for Wound Infection After Ileostomy for Rectal Cancer and Its Relationship with Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 (NLRP3) Gene Polymorphism

Huan Ren, Bing Zhang, Peidian Shi, Ruizhe Shi et al.
Infection and Drug Resistance
Immune Response and Inflammation
article

Construction of a Risk Factor Model for Wound Infection After Ileostomy for Rectal Cancer and Its Relationship with Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 (NLRP3) Gene Polymorphism

Huan Ren, Bing Zhang, Peidian Shi, Ruizhe Shi, Fanke Wang, Yan Zhou, Ming Wei, Jianling Yang, Yang Li
article en

Abstract

This study identified the independent risk factors for postoperative wound infection. Patients with the G allele have a higher risk of postoperative infection, and <i>NLRP3</i> gene polymorphism is closely associated with the risk factors included in the model. The association between <i>NLRP3</i> gene polymorphisms and the risk of postoperative infection provides a new molecular biological indicator for prognostic evaluation.

Infection and Drug ResistanceVol. Volume 18
Hebei Medical University (CN), Third Hospital of Hebei Medical University (CN), Second Hospital of Hebei Medical University (CN), Bethune International Peace Hospital (CN), First Affiliated Hospital of Hebei Medical University (CN)
Openalex Percentile: Top 55%
Immune Response and Inflammation
DOIOpen Access PDFOpenAlex
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Construction of a Risk Factor Model for Wound Infection After Ileostomy for Rectal Cancer and Its Relationship with Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 (NLRP3) Gene Polymorphism — Huan Ren, Bing Zhang, et al. · Infection and Drug Resistance (2025) | TGRS Research Map | TGRS