Asiatic acid inhibits NF-κB signaling and ameliorates experimental acute and chronic colitis in mice
AA alleviates intestinal inflammation by suppressing NF-κB signaling in vitro and exhibits therapeutic efficacy in both acute and chronic colitis models, suggesting its potential as a therapeutic candidate for inflammatory bowel disease.
Authors
- Seong‐Joon Koh (ORCID: https://orcid.org/0000-0001-8001-8777)
- Jong Pil Im (ORCID: https://orcid.org/0000-0003-1584-0160)
- Hyun Jung Lee (ORCID: https://orcid.org/0000-0002-9941-9826)
- Joo Sung Kim (ORCID: https://orcid.org/0000-0001-6835-4735)
- Seona Park (ORCID: https://orcid.org/0000-0002-7281-0833)
Institutions
- Seoul National University (KR)
- Sejong General Hospital (KR)
- Incheon Medical Center (KR)
Publication Details
- Journal
- International Journal of Immunopathology and Pharmacology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1177/03946320251398285
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.00