Visual Disturbances Associated With Statins: A Case Report and Literature Review

Statins are a class of drugs that are vital for lowering blood lipid levels and reducing the risk of both primary and secondary cardiovascular diseases. These drugs are generally considered safe; however, some individuals may experience side effects, such as muscle pain, headache, fatigue, myopathy, and gastrointestinal disorders. One of the less frequently reported side effects of statins is visual disturbances. We report the case of a 51-year-old woman who developed persistent headache, blurred vision, and diplopia shortly after initiating Atorvastatin. These visual disturbances recurred when treatment was switched to Rosuvastatin and Lovastatin. Comprehensive neurological evaluation, including brain MRI, was unremarkable. All symptoms resolved completely after permanent discontinuation of statin therapy, indicating a rare but significant statin-associated visual adverse event. Due to the significance of reporting this complication, this study aims to present a case of a patient who experienced visual impairment associated with the use of atorvastatin, rosuvastatin, and, to a lesser extent, lovastatin.

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Journal
Clinical Medicine Insights Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1177/11795476251400972
Citations
1
Primary Topic
Drug-Induced Ocular Toxicity
Type
article
Field-Weighted Citation Impact
1.71
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article

Visual Disturbances Associated With Statins: A Case Report and Literature Review

Abdolamir Atapour, Mahnaz Momenzadeh, Mahsa Panahishokouh
1 citations
Clinical Medicine Insights Case Reports
Drug-Induced Ocular Toxicity
1.71
article

Visual Disturbances Associated With Statins: A Case Report and Literature Review

Abdolamir Atapour, Mahnaz Momenzadeh, Mahsa Panahishokouh
article en
1 citations

Abstract

Statins are a class of drugs that are vital for lowering blood lipid levels and reducing the risk of both primary and secondary cardiovascular diseases. These drugs are generally considered safe; however, some individuals may experience side effects, such as muscle pain, headache, fatigue, myopathy, and gastrointestinal disorders. One of the less frequently reported side effects of statins is visual disturbances. We report the case of a 51-year-old woman who developed persistent headache, blurred vision, and diplopia shortly after initiating Atorvastatin. These visual disturbances recurred when treatment was switched to Rosuvastatin and Lovastatin. Comprehensive neurological evaluation, including brain MRI, was unremarkable. All symptoms resolved completely after permanent discontinuation of statin therapy, indicating a rare but significant statin-associated visual adverse event. Due to the significance of reporting this complication, this study aims to present a case of a patient who experienced visual impairment associated with the use of atorvastatin, rosuvastatin, and, to a lesser extent, lovastatin.

Clinical Medicine Insights Case ReportsVol. 18
Isfahan University of Medical Sciences (IR)
Openalex Percentile: Top 12%
Drug-Induced Ocular Toxicity
1.71
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Visual Disturbances Associated With Statins: A Case Report and Literature Review — Abdolamir Atapour, Mahnaz Momenzadeh, et al. · Clinical Medicine Insights Case Reports (2025) | TGRS Research Map | TGRS