The Use of Parabulbar and Sub‐Tenon Injections to Correct Isolated Resistant Diplopia in Patients With Generalized Myasthenia Gravis: A Long Road to Clinically Meaningful Success

Parabulbar betamethasone provided rapid and durable relief of isolated, treatment-resistant diplopia in seronegative myasthenia gravis after multiple systemic therapy failures, suggesting that targeted periocular corticosteroid delivery may be a steroid-sparing option for carefully selected patients when standard treatments are ineffective and close ophthalmic monitoring is available.

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Publication Details

Journal
Clinical Case Reports
Published
2025-12-01
DOI
https://doi.org/10.1002/ccr3.71573
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
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article

The Use of Parabulbar and Sub‐Tenon Injections to Correct Isolated Resistant Diplopia in Patients With Generalized Myasthenia Gravis: A Long Road to Clinically Meaningful Success

Margarita Marchuk, Volodymyr Sanin, Maksym Zinchenko, Vladyslav Mamilov
Clinical Case Reports
Myasthenia Gravis and Thymoma
article

The Use of Parabulbar and Sub‐Tenon Injections to Correct Isolated Resistant Diplopia in Patients With Generalized Myasthenia Gravis: A Long Road to Clinically Meaningful Success

Margarita Marchuk, Volodymyr Sanin, Maksym Zinchenko, Vladyslav Mamilov
article en

Abstract

Parabulbar betamethasone provided rapid and durable relief of isolated, treatment-resistant diplopia in seronegative myasthenia gravis after multiple systemic therapy failures, suggesting that targeted periocular corticosteroid delivery may be a steroid-sparing option for carefully selected patients when standard treatments are ineffective and close ophthalmic monitoring is available.

Clinical Case ReportsVol. 13(12)
Kyiv City Clinical Oncology Center (UA), Kyiv National Economic University named after Vadym Hetman (UA), Bogomolets National Medical University (UA)
Openalex Percentile: Top 46%
Myasthenia Gravis and Thymoma
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