Case Report: Bone Marrow Infiltration with Anemia and Thrombocytopenia, Rare Initial Symptoms of Breast Cancer

Bone marrow infiltration causing pancytopenia is a rare but serious manifestation of metastatic breast cancer. Management should follow general principles for metastatic breast cancer. Chemotherapy can be considered when rapid disease control is needed or in patients with marrow failure, provided that doses are individualized and treatment is closely monitored. Further data are required to better define optimal therapy in this setting.