Impact of Age, Sex, and Race on Primary Aldosteronism Test Interpretations
In this large, diverse, nationwide sample, older and Black participants had higher aldosterone-to-renin ratio and higher odds of testing positive for PA, and women had higher aldosterone levels than men across the lifespan. With newly expanded indications for PA testing, a greater appreciation of the influence of demographic characteristics on PA test results will be required.
Authors
- Stéfanie Parisien‐La Salle (ORCID: https://orcid.org/0000-0001-5960-4181)
- Shant H. Mahrokhian (ORCID: https://orcid.org/0000-0003-4094-8739)
- Kevin M. Foote (ORCID: https://orcid.org/0000-0001-6509-0316)
- Anand Vaidya (ORCID: https://orcid.org/0000-0002-0314-9252)
- Cheng‐Hsuan Tsai (ORCID: https://orcid.org/0000-0003-2859-5117)
- Isabelle Hanna (ORCID: https://orcid.org/0009-0009-5968-1406)
- Jenifer M. Brown (ORCID: https://orcid.org/0000-0002-6647-639X)
- Laura C Tsai (ORCID: https://orcid.org/0009-0008-5344-2589)
- Justin M. Chan (ORCID: https://orcid.org/0009-0006-6265-1425)
- E Abel
- Andrew J Newman (ORCID: https://orcid.org/0000-0002-8326-1964)
- Arnaldo Ferrebus (ORCID: https://orcid.org/0009-0009-0558-2154)
Institutions
- Brigham and Women's Hospital (US)
- National Taiwan University Hospital (TW)
- Centre Hospitalier de l’Université de Montréal (CA)
Publication Details
- Journal
- Hypertension
- Published
- 2025-12-10
- DOI
- https://doi.org/10.1161/hypertensionaha.125.25855
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00