Evaluation of F18 enterotoxigenic Escherichia coli intestinal attachment and early disease onset in nursery pigs
A 5-day F18 ETEC challenge induced ETEC attachment and diarrhea. These findings support a model where F18 ETEC epithelial attachment drives diarrhea through an enterotoxin-mediated, CFTR-dependent secretory mechanism rather than structural epithelial damage.
Authors
- Nicholas K Gabler (ORCID: https://orcid.org/0000-0001-7283-4782)
- Emma T Helm (ORCID: https://orcid.org/0000-0002-8025-9690)
- Eric Ryan Burrough (ORCID: https://orcid.org/0000-0003-4747-9189)
- Elizabeth M Due
- Kayla A Miller
Institutions
- Iowa State University (US)
- Virginia Tech (US)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fvets.2025.1686769
- Citations
- 1
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 1.80
Funders
- U.S. Department of Agriculture
- Iowa State University
- National Institute of Food and Agriculture