The ratio of GGT to PLT indices is a predictive factor for the progression of liver fibrosis in NA-treated chronic hepatitis B patients with advanced fibrosis plus PEG-IFN α-2a therapy: a case–control study
Approximately one-fifth of the NA-treated CHB patients with advanced liver fibrosis and compensated cirrhosis experienced progression of liver fibrosis after PEG-IFN α-2a treatment. The GPR at 24 weeks of treatment was an independent predictive factor for the progression of liver fibrosis in this population.
Authors
- Xiucheng Pan (ORCID: https://orcid.org/0000-0001-9706-9458)
- Lijun Shi (ORCID: https://orcid.org/0000-0001-6655-2949)
- Guojun Li (ORCID: https://orcid.org/0000-0001-9505-1502)
- Huili Li (ORCID: https://orcid.org/0000-0001-9316-4087)
- Yiru Zhao (ORCID: https://orcid.org/0000-0003-2248-4440)
- Ling Li (ORCID: https://orcid.org/0000-0003-1493-9687)
- Liying Ren (ORCID: https://orcid.org/0009-0005-8000-3950)
- Mireyi Suwanbai
Institutions
- Xuzhou Medical College (CN)
- Longgang Central Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.1186/s12876-025-04508-4
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00