Aripiprazole and <i>CYP2D6</i> : A retrospective cohort study evaluating the impact of phenotype on metabolic abnormalities

This study suggests that the incidence of metabolic abnormalities beyond LDL may not be higher in CYP2D6 poor metabolizers compared to normal metabolizers. Further research is needed to investigate clinically meaningful outcomes in relation to CYP2D6 and aripiprazole.

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Publication Details

Journal
American Journal of Health-System Pharmacy
Published
2025-12-09
DOI
https://doi.org/10.1093/ajhp/zxaf345
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Aripiprazole and CYP2D6 : A retrospective cohort study evaluating the impact of phenotype on metabolic abnormalities

Brian Meissner, F. Younes, Natasha Petry, Amanda Massmann et al.
American Journal of Health-System Pharmacy
Pharmacogenetics and Drug Metabolism
article

Aripiprazole and CYP2D6 : A retrospective cohort study evaluating the impact of phenotype on metabolic abnormalities

Brian Meissner, F. Younes, Natasha Petry, Amanda Massmann, Max Weaver
article en

Abstract

This study suggests that the incidence of metabolic abnormalities beyond LDL may not be higher in CYP2D6 poor metabolizers compared to normal metabolizers. Further research is needed to investigate clinically meaningful outcomes in relation to CYP2D6 and aripiprazole.

American Journal of Health-System Pharmacy
Sanford Health (US), University of South Dakota (US), Sanford Medical Center (US), Sanford Medical Center (US)
Openalex Percentile: Top 52%
Pharmacogenetics and Drug Metabolism
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Aripiprazole and <i>CYP2D6</i> : A retrospective cohort study evaluating the impact of phenotype on metabolic abnormalities — Brian Meissner, F. Younes, et al. · American Journal of Health-System Pharmacy (2025) | TGRS Research Map | TGRS