Anesthetic Management of a Dental Patient With Familial Mediterranean Fever

We present the anesthetic management of a 32-year-old patient diagnosed with familial Mediterranean fever (FMF) who underwent dental surgery. To minimize the risk of triggering an FMF attack, careful perioperative planning was implemented. Key preventive measures included avoiding known FMF triggers like cold exposure as well as maintaining stable vital signs and ensuring close temperature control throughout the procedure. The patient had shown resistance to colchicine therapy in the past, necessitating careful consideration of alternative treatments, including the potential use of IL-1 inhibitors. General anesthesia was successfully administered without inducing an FMF acute attack. Effective postoperative pain management was provided, and no FMF-related complications arose during the recovery period. This successful outcome highlights the importance of close collaboration and ongoing communication with the patient's primary physician and specialists familiar with FMF. Achieving safe anesthetic management for patients with FMF requires meticulous perioperative planning, proactive avoidance of potential FMF triggers, and a collaborative approach across disciplines. These elements are essential to preventing perioperative FMF exacerbations and ensuring smooth, complication-free recovery for patients.

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Publication Details

Journal
Anesthesia Progress
Published
2025-12-01
DOI
https://doi.org/10.2344/24-0048
Primary Topic
Inflammasome and immune disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Anesthetic Management of a Dental Patient With Familial Mediterranean Fever

Akihiro Kawauchi, Ayumi Nakayama, Shin-ichi Sato, Shigeru Maeda et al.
Anesthesia Progress
Inflammasome and immune disorders
article

Anesthetic Management of a Dental Patient With Familial Mediterranean Fever

Akihiro Kawauchi, Ayumi Nakayama, Shin-ichi Sato, Shigeru Maeda, Masami Hasegawa
article en

Abstract

We present the anesthetic management of a 32-year-old patient diagnosed with familial Mediterranean fever (FMF) who underwent dental surgery. To minimize the risk of triggering an FMF attack, careful perioperative planning was implemented. Key preventive measures included avoiding known FMF triggers like cold exposure as well as maintaining stable vital signs and ensuring close temperature control throughout the procedure. The patient had shown resistance to colchicine therapy in the past, necessitating careful consideration of alternative treatments, including the potential use of IL-1 inhibitors. General anesthesia was successfully administered without inducing an FMF acute attack. Effective postoperative pain management was provided, and no FMF-related complications arose during the recovery period. This successful outcome highlights the importance of close collaboration and ongoing communication with the patient's primary physician and specialists familiar with FMF. Achieving safe anesthetic management for patients with FMF requires meticulous perioperative planning, proactive avoidance of potential FMF triggers, and a collaborative approach across disciplines. These elements are essential to preventing perioperative FMF exacerbations and ensuring smooth, complication-free recovery for patients.

Anesthesia ProgressVol. 72(4)
Tokyo Medical and Dental University (JP), Sanford Medical Center (US)
Openalex Percentile: Top 64%
Inflammasome and immune disorders
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