Comparison of Esmolol Versus Landiolol on Mortality in Adult Patients With Sepsis: A Systematic Review and Network Meta-Analysis
Among patients with sepsis treated with β-blockers, esmolol probably improves clinical outcomes compared with SOC. However, the effect of landiolol remains uncertain due to the low certainty of evidence. Esmolol may confer a relative clinical advantage over landiolol, but further studies are needed to confirm this finding and elucidate the underlying mechanisms.
Authors
- Zhaoqing Tang (ORCID: https://orcid.org/0000-0001-5286-6330)
- Qin Sun
- Fei Peng (ORCID: https://orcid.org/0000-0002-5446-9854)
- Yi Yang (ORCID: https://orcid.org/0000-0002-8660-3501)
- Jingyuan Xu (ORCID: https://orcid.org/0000-0003-1240-4929)
Institutions
- Zhongda Hospital Southeast University (CN)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1097/ccm.0000000000006966
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Southeast University
- National Key Research and Development Program of China