The effect of psychopharmacological load on various aspects of the condition in patients with depressive syndrome during remission

The combination of relatively high doses of antidepressants with subtherapeutic doses of antipsychotic agents has the most multifaceted effect. Moderate cholinolytic load does not affect the cognitive performance of patients, but reduces their social cognition in terms of emotion attribution in the context of social interaction.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2025-12-09
DOI
https://doi.org/10.17116/jnevro202512511169
Primary Topic
Neurological Disorders and Treatments
Type
article
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article

The effect of psychopharmacological load on various aspects of the condition in patients with depressive syndrome during remission

G. Rupchev, Morozova Ma, E.Y. Nikonova, G Ch Ashurova et al.
S S Korsakov Journal of Neurology and Psychiatry
Neurological Disorders and Treatments
article

The effect of psychopharmacological load on various aspects of the condition in patients with depressive syndrome during remission

G. Rupchev, Morozova Ma, E.Y. Nikonova, G Ch Ashurova, V V Trushkova, A Yu Radchenko, N S Petukhova
article en

Abstract

The combination of relatively high doses of antidepressants with subtherapeutic doses of antipsychotic agents has the most multifaceted effect. Moderate cholinolytic load does not affect the cognitive performance of patients, but reduces their social cognition in terms of emotion attribution in the context of social interaction.

S S Korsakov Journal of Neurology and PsychiatryVol. 125(11)
Lomonosov Moscow State University (RU), Centre for Mental Health (GB), Clinical Hospital No. 8 (RU), Moscow State University (TJ), Mental Health Research Center of Russian Academy of Medical Sciences (RU)
Openalex Percentile: Top 54%
Neurological Disorders and Treatments
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