Semantic networks in relapsing-remitting multiple sclerosis exhibit reduced efficiency, interconnectivity, and flexibility

Word-finding concerns are prevalent in pwRRMS; it is important to screen for and address these concerns in clinical settings. Semantic network analysis appears more sensitive in detecting semantic retrieval deficits in pwRRMS relative to standard semantic fluency metrics. Semantic network disorganization and inflexibility may partially underlie word-finding difficulty in pwRRMS. Strategies aimed at improving network structure may assist in managing these deficits.