Feasibility and Diagnostic Utility of Mucosal T-cell Flow Cytometry for Intestinal Graft-versus-Host Disease
Mucosal T-cell profiling using endoscopic biopsies is feasible and may aid in the diagnosis of GVHD after HSCT. A decreased CD56<sup>+</sup>:CD3<sup>+</sup> ratio is a promising marker for distinguishing GVHD from other post-transplant intestinal conditions.
Authors
- Masaya Iwamuro (ORCID: https://orcid.org/0000-0002-1757-5754)
- Nobuharu Fujii (ORCID: https://orcid.org/0000-0002-8043-7768)
- Yoshinobu Maeda (ORCID: https://orcid.org/0000-0003-1634-5487)
- Araki Hirabata
- Takumi Kondo (ORCID: https://orcid.org/0000-0002-6395-7913)
- Takehiro Tanaka (ORCID: https://orcid.org/0000-0002-1509-5706)
- Motoyuki Otsuka (ORCID: https://orcid.org/0000-0003-2869-2881)
- Daisuke Ennishi (ORCID: https://orcid.org/0000-0003-4788-2103)
- Takahide Takahashi (ORCID: https://orcid.org/0000-0002-4084-1854)
- M. Hiramatsu
Institutions
- Okayama University (JP)
- Okayama University Hospital (JP)
Publication Details
- Journal
- Gastro Hep Advances
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.gastha.2025.100820
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00