Consensus Opinion on Safe Injection Technique and Management of PDLLA-HA200-Induced Visual Impairment
Poly-D,L-lactic acid with hyaluronic acid (PDLLA-HA) represents a next-generation injectable combining the collagen-stimulating property of poly-D,L-lactic acid (PDLLA) microspheres with non-cross-linked hyaluronic acid (HA) as a carrier. One rare but devastating complication is visual field impairment and blindness due to inadvertent intravascular injection. Recognizing the need for a dedicated consensus on the management of PDLLA-HA-induced visual impairment, a panel of experts comprising oculoplastic surgeons, dermatologists, and aesthetic physicians was convened to give a consensus on safe practice with PDLLA-HA 200 (Juvelook Volume/Lenisna) and develop a management algorithm for the management of PDLLA-HA-induced blindness.
Authors
- Mariel Angelou Parulan (ORCID: https://orcid.org/0000-0002-2628-9805)
- K.‐H. William Lau (ORCID: https://orcid.org/0000-0003-1109-5052)
- Stephanie Ming Young (ORCID: https://orcid.org/0000-0001-8223-342X)
- Alice Goh
- Kyu‐Ho Yi (ORCID: https://orcid.org/0000-0001-5572-1364)
- Maria Cristina A Puyat
- Nilesh H Pawar
- Elaine Co
- Michelle Marie P Supapo
- Nazelia Binti Thibroni
- Isabella Rosellini
Institutions
- RCSI & UCD Malaysia Campus (MY)
- Yonsei University (KR)
- Lung Center of the Philippines (PH)
- Penang Adventist Hospital (MY)
- St. Luke's Medical Center (PH)
- Intel (Malaysia) (MY)
- Eagle Mount (US)
- Beaumont Hospital (US)
- Clinical Nutrition Research Centre (SG)
- Yonsei University College of Dentistry
- University of Asia and the Pacific (PH)
Publication Details
- Journal
- Journal of Craniofacial Surgery
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1097/scs.0000000000012271
- Primary Topic
- Facial Rejuvenation and Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00