The effect of inflammation on sexual desire and sexual function in pre- and post-menopausal women is moderated by sexual violence history

CRP was not associated with subjective sexual arousal or sexual functioning in a sample of healthy women; further work may identify if more sensitive inflammation biomarkers are needed, or if inflammation has greater effects on sexual function in specific conditions such metabolic syndrome. Of note, CRP did predict lower sexual desire in women with sexual violence histories, suggesting that survivors of sexual violence may be particularly sensitive to inflammation-mediation suppression of sexual motivation and/or reward.

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Publication Details

Journal
The Journal of Sexual Medicine
Published
2025-11-25
DOI
https://doi.org/10.1093/jsxmed/qdaf347
Primary Topic
Sexual function and dysfunction studies
Type
article
Field-Weighted Citation Impact
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article

The effect of inflammation on sexual desire and sexual function in pre- and post-menopausal women is moderated by sexual violence history

Tierney K. Lorenz, Kirstin Clephane, Marc Grosserueschkamp
The Journal of Sexual Medicine
Sexual function and dysfunction studies
article

The effect of inflammation on sexual desire and sexual function in pre- and post-menopausal women is moderated by sexual violence history

Tierney K. Lorenz, Kirstin Clephane, Marc Grosserueschkamp
article en

Abstract

CRP was not associated with subjective sexual arousal or sexual functioning in a sample of healthy women; further work may identify if more sensitive inflammation biomarkers are needed, or if inflammation has greater effects on sexual function in specific conditions such metabolic syndrome. Of note, CRP did predict lower sexual desire in women with sexual violence histories, suggesting that survivors of sexual violence may be particularly sensitive to inflammation-mediation suppression of sexual motivation and/or reward.

The Journal of Sexual MedicineVol. 23(1)
University of Nebraska–Lincoln (US), Humboldt-Universität zu Berlin (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 54%
Sexual function and dysfunction studies
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The effect of inflammation on sexual desire and sexual function in pre- and post-menopausal women is moderated by sexual violence history — Tierney K. Lorenz, Kirstin Clephane, et al. · The Journal of Sexual Medicine (2025) | TGRS Research Map | TGRS