Short-Term Viability and Extracellular Matrix Integrity of Autologous Septal Cartilage Stored at −40°C Without a Preservative

Short-term storage of autologous septal cartilage at -40 °C without a preservative maintains substantial histological and cellular integrity. Nonetheless, longer storage durations lead to gradual ECM degradation and decreased chondrocyte viability. These findings highlight the importance of optimizing storage duration to preserve the structural and functional reliability of cartilage grafts in revision septorhinoplasty.

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Publication Details

Journal
Aesthetic Surgery Journal
Published
2025-12-07
DOI
https://doi.org/10.1093/asj/sjaf256
Primary Topic
Nasal Surgery and Airway Studies
Type
article
Field-Weighted Citation Impact
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article

Short-Term Viability and Extracellular Matrix Integrity of Autologous Septal Cartilage Stored at −40°C Without a Preservative

Mehmet Hakan Korkmaz, Hasan Furkan Çaycı, Ömer Kaplan, Naile Kökbudak et al.
Aesthetic Surgery Journal
Nasal Surgery and Airway Studies
article

Short-Term Viability and Extracellular Matrix Integrity of Autologous Septal Cartilage Stored at −40°C Without a Preservative

Mehmet Hakan Korkmaz, Hasan Furkan Çaycı, Ömer Kaplan, Naile Kökbudak, Malik Afifoğlu, Fakih Cihat Eravci, İbrahim Kolukisa
article en

Abstract

Short-term storage of autologous septal cartilage at -40 °C without a preservative maintains substantial histological and cellular integrity. Nonetheless, longer storage durations lead to gradual ECM degradation and decreased chondrocyte viability. These findings highlight the importance of optimizing storage duration to preserve the structural and functional reliability of cartilage grafts in revision septorhinoplasty.

Aesthetic Surgery Journal
Bursa Technical University (TR), State Hospital (GB), Yenişehir Hospital (TR), Necmettin Erbakan University (TR), S.B.Ü. Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi (TR)
Openalex Percentile: Top 41%
Nasal Surgery and Airway Studies
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Short-Term Viability and Extracellular Matrix Integrity of Autologous Septal Cartilage Stored at −40°C Without a Preservative — Mehmet Hakan Korkmaz, Hasan Furkan Çaycı, et al. · Aesthetic Surgery Journal (2025) | TGRS Research Map | TGRS