Pre-treatment journey and outcome for children with intracranial non-germinomatous germ cell tumors—the Shanghai experience
Standardized multidisciplinary treatment achieves favorable outcomes comparable to international benchmarks. Aggressive surgery does not improve survival when tumor markers normalize. Diagnostic delays remain common, emphasizing the need for improved awareness and referral systems in China.
Authors
- Bo Yang (ORCID: https://orcid.org/0000-0001-9268-8436)
- An‐An Zhang (ORCID: https://orcid.org/0000-0001-8439-2707)
- Yijin Gao (ORCID: https://orcid.org/0000-0002-7592-4115)
- Ibrahim A. Qaddoumi (ORCID: https://orcid.org/0000-0002-6645-4895)
- Haiyan Chen (ORCID: https://orcid.org/0000-0003-0093-0366)
- Xiang Huang (ORCID: https://orcid.org/0000-0002-4335-2837)
- Rong Zhang (ORCID: https://orcid.org/0000-0001-8019-245X)
- Xiaolong Chen (ORCID: https://orcid.org/0000-0002-9301-4246)
- Anthony Pak‐Yin Liu
Institutions
- St. Jude Children's Research Hospital (US)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Hospital for Sick Children (CA)
- Shanghai Children's Medical Center (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-12-06
- DOI
- https://doi.org/10.1093/noajnl/vdaf254
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00