Highly Reliable and Ultraflexible Organic Light‐Emitting Diode Patch for Psoriasis Treatment
Psoriasis is a chronic inflammatory skin disease that significantly affects the quality of life of patients. Photodynamic therapy is effective in treating psoriasis; however, existing light sources, such as lasers and light-emitting diodes (LEDs), have limitations in terms of flexibility, uniformity of light irradiation, and patient convenience. In this study, a high-power ultraflexible organic LED (OLED) patch is fabricated on a PET adhesive film, resulting in a high output of 60 mW cm<sup>-2</sup> at 7.5 V. Based on high-performance encapsulation technology, the OLED patch achieved a lifetime of 177 h and no performance change after bending for 10 000 times for a radius of 2 mm at 35 mW cm<sup>-2</sup>. Finally, photodynamic therapy is performed in a psoriasis mouse model using an OLED for the first time, and the effect is confirmed through a cross-sectional analysis of the mouse skin, in which the thickness of the diseased area is reduced by 66% compared with the control group.
Authors
- Kyung Cheol Choi (ORCID: https://orcid.org/0000-0001-6483-9516)
- Sangyong Jon (ORCID: https://orcid.org/0000-0002-6971-586X)
- Ilkoo Noh (ORCID: https://orcid.org/0000-0001-7721-4662)
- Changjin Seo
- Yongmin Jeon (ORCID: https://orcid.org/0000-0002-5607-3642)
- Yutaek Seo (ORCID: https://orcid.org/0000-0001-8537-579X)
- Jeong Hyun Kwon (ORCID: https://orcid.org/0000-0002-1336-6242)
Institutions
- Korea Advanced Institute of Science and Technology (KR)
- Chungbuk National University (KR)
- Kangwon National University (KR)
- Kyung Hee University (KR)
Publication Details
- Journal
- Advanced Healthcare Materials
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1002/adhm.202504410
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00