Genomic and phenotypic characterization of two novel human-derived Limosilactobacillus reuteri strains with unique probiotic traits
This study expands the genomic repository of <i>L. reuteri</i> and provides clear experimental evidence of strain-specific functional profiles. Our findings establish a foundation for the precision selection of <i>L. reuteri</i> strains such as LLR2 for gut barrier reinforcement and LLR3 for inflammation modulation in tailored applications for gut health and gut-brain axis research.
Authors
- Lijuan Yang
- Aoqi Wang
- Yongjun Lu (ORCID: https://orcid.org/0000-0002-3030-5724)
- Zhenhuang Ge (ORCID: https://orcid.org/0000-0002-1189-7285)
- Jinjin Li (ORCID: https://orcid.org/0000-0002-0234-1533)
- Hongyu Zhan
- Yi Zou
- Xiaoyu Wu (ORCID: https://orcid.org/0000-0003-3115-673X)
Institutions
- Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fmicb.2025.1723084
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sun Yat-sen University
- Fundamental Research Funds for the Central Universities
- Basic and Applied Basic Research Foundation of Guangdong Province