RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking
RPL41 down-regulates the expression of ARL5B by degrading ATF4 and the impaired ARL5B-related lysosomal trafficking is a mechanism to inhibit the metastasis of retinoblastoma.
Authors
- Qianwen Zhong
- T.-C. Chen
- Yisheng Jiao (ORCID: https://orcid.org/0000-0001-6198-7492)
- Tian Zhan
- Ye Li (ORCID: https://orcid.org/0000-0001-7727-0875)
- Yu Wang (ORCID: https://orcid.org/0000-0001-7811-5834)
- Sheng Xiao (ORCID: https://orcid.org/0000-0001-6458-2490)
Institutions
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fimmu.2025.1704080
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 0.00