pH-regulated nuclear F-actin assembly during ferroptosis
These findings reveal nuclear F-actin assembly driven by cytoplasmic actin remodeling, nuclear import, and intracellular acidification, uncovering a previously unrecognized feature of ferroptotic cell death.
Authors
- Lingbo Cao
- Zhipeng Yan (ORCID: https://orcid.org/0000-0002-1007-4287)
- Yun‐Miao Guo
- Haiying Mai
- Yu Fang (ORCID: https://orcid.org/0000-0003-2438-3678)
- Junqi Huang (ORCID: https://orcid.org/0000-0002-0901-9635)
- Na Li (ORCID: https://orcid.org/0000-0002-0789-0515)
- J. Huang (ORCID: https://orcid.org/0009-0007-0166-8124)
- Maiju Qiao (ORCID: https://orcid.org/0000-0001-8327-5891)
- Kun Xu (ORCID: https://orcid.org/0000-0003-4550-6622)
Institutions
- Central People's Hospital of Zhanjiang (CN)
- Regenerative Medicine Institute (MX)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fcell.2025.1699698
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China
- Jinan University
- Basic and Applied Basic Research Foundation of Guangdong Province