The impact of methylprednisolone and rituximab on podocyte injury caused by puromycin aminonucleoside
Therefore, MP and RTX safeguarded podocytes, and averted proteinuria by decreasing podocyte apoptosis, diminishing TRPC6 mRNA and protein levels, and suppressing inflammatory markers and calcium entry.
Authors
- Ying Jie Zhu (ORCID: https://orcid.org/0000-0003-0418-919X)
- Fang Deng (ORCID: https://orcid.org/0000-0002-7927-5394)
- Manman Zhao (ORCID: https://orcid.org/0000-0002-4448-8816)
- Li Wang (ORCID: https://orcid.org/0000-0002-0910-0361)
- Ran Hua
- Jialiang Zhu (ORCID: https://orcid.org/0000-0001-7142-8467)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Anhui Provincial Children's Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-12-10
- DOI
- https://doi.org/10.3389/fcell.2025.1504834
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Medical University